Get the latest posts from Dr Jonathan Reed on your
Yahoo! Home Page. ![]()
Archives
- January 2012
- June 2011
- May 2011
- April 2011
- January 2011
- October 2010
- July 2010
- May 2010
- April 2010
- March 2010
- February 2010
- January 2010
- November 2009
- October 2009
- September 2009
- July 2009
- June 2009
- May 2009
- April 2009
- March 2009
- February 2009
- January 2009
- December 2008
- November 2008
- October 2008
- September 2008
Recent Articles
- 5 apps that help improve motor co-ordination whilst having fun
- Achieving total memory recall
- 10 Computer Games that are good for your brain
- What makes a good educational ipad app
- How to improve memory
- The return of the unconscious mind
- A new way of looking at how the brain works
- Play and the iPad: a new direction for Games Based Learning?
- Brain injury and creativity
- Casual games that are educational
Categories
- abuse
- adhd
- adhd treatment
- apple
- asperger's
- autism
- behaviour
- brain development
- brain injury
- brain training
- casual gaming
- computer game based learning
- computer games
- development
- dyscalculia
- dyslexia
- dyslexia treatment
- education
- empathy
- fish oil
- genes
- head injury
- IQ
- malcolm gladwell
- maths
- memory
- multiple sclerosis
- murder
- neglect
- neurogames
- neuroscience
- parenting
- personality
- physical disability
- physiotherapy
- poverty
- prevention
- rehabiliatation
- RTI
- speech and language impairment
- stem cells
- subcortical function
- technology
- Uncategorized
- violent behaviour
- web
- working memory
-
Neurogenetics and language
No CommentsOne of the fastest moving and most exciting areas in developmental neuroscience is neurogenetics. The key is to understand how genes produce the proteins that make up the brain and how they in turn affect behaviour. This week a study published in The New England Journal of Medicine looks at the role of a specific gene in Specific Language Impairment (SLI)- see study details here. The researchers have found that the gene CNTNAP2 is associated with performance on a non word repetition task which is a behavioural marker for SLI. The gene seems to have a role in brain development and more specifically in enrichment of frontal gray matter. I have to say I am really surprised by these findings. I tend to take the view that Professor Robert Plomin at the Institute of Psychiatry takes which is that genes are likely to be more general in their effects with genes likely to mainly effect several different brain areas and functions. This would make sense from a biological and evolutionary perspective. He and his colleague Yulia Kovas have written a good summary about these issues in our Child Neuropsychology book. My understanding is that language development is a very dynamic process involving many brain areas at first and then fixing in set areas. If these set areas are damaged language can still develop in different brain areas. I am not sure how damage to one area of the brain from birth due to genes would have such a specific effect. Also I would be amazed if this brain area affected by this gene just affected such a specific task as non word repetition- I am sure that it would affect other functions as well. The paper is however detailed in terms the genes involved, the brain areas they affect and the behaviours that are affected as a result. We will need to see whether the findings are replicated and whether they generalise. A previous very promising finding by the same research group which suggested that the FOXP2 gene was involved in language disorder proved to only relate to a few very unusual cases. Over the next few years expect to see increasing research into neurogenetics. Some of these findings are likely to challenge the way we understand child development. It should lead to a revolution in our understanding of child disorders and how to treat them. It is an exciting time for child neuropsychology.
Published on November 7, 2008 · Filed under: genes, speech and language impairment; Tagged as: genes, speech and language impairment


